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  • 分类:近期动态
  • 发布时间:2022-05-17 09:57:55
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       作为一个科学家成立的科研服务机构,华盈生物的主要荣耀来自于能够帮助越来越多的科学家合作伙伴在高质量的国际期刊上刊发重要研究成果。不忘初心牢记使命,为中国生物医学基础研究的腾飞,作出一个高品质企业应有的贡献。自2012年成立以来,华盈生物“科学家服务科学家”的经营理念和严谨务实的经营态度受到越来越多中国学者群体的认可,我们服务的客户几乎覆盖了中国生物医学研究领域所有重点高效和院所,先后为院士、长江学者、杰青等众多杰出科学家及其研究团队提供过高质量的科研数据支持。现列举部分客户发表的文章如下:

2022年:

1. Bing Yao, Sha Zhu, Xiyi Wei, et al. The circSPON2/miR-331-3p axis regulates PRMT5, an epigenetic regulator of CAMK2N1 transcription and prostate cancer progression.Mol Cancer. 2022 May 27;21(1):119.  (南方医科大学&南京医科大学)

2. Zhou WJ, et al. Fructose-1,6-bisphosphate prevents pregnancy loss by inducing decidual COX-2+ macrophage differentiation. Sci Adv. 2022 Feb 25;8(8):eabj2488. (复旦大学附属妇产科医院)

3. Wang G, et al. Icariin alleviates uveitis by targeting peroxiredoxin 3 to modulate retinal microglia M1/M2 phenotypic polarization. Redox Biol. 2022 Jun;52:102297.(重庆医科大学)

4. Zhu Y, et al. LncRNA LINC00942 promotes chemoresistance in gastric cancer by suppressing MSI2 degradation to enhance c-Myc mRNA stability. Clin Transl Med. 2022 Jan;12(1):e703.(浙江大学医学院附属邵逸夫医院)

5. Geng YJ, et al. Long-term exposure to genistein inhibits the proliferation of gallbladder cancer by downregulating the MCM complex.Science Bulletin.2022 April;67(8):813-824.(上海交通大学附属仁济医院)

6. Du C, et al. Renal Klotho and inorganic phosphate are extrinsic factors that antagonistically regulate hematopoietic stem cell maintenance. Cell Rep. 2022 Feb 15;38(7):110392.(第三军医大学)

7. Zhu D, et al. Tubulin-binding peptide RR-171 derived from human umbilical cord serum displays antitumor activity against hepatocellular carcinoma via inducing apoptosis and activating the NF-kappa B pathway. Cell Prolif. 2022 May 3:e13241.(第四军医大学西京医院)

8. Zheng Z, et al. Bone marrow mesenchymal stem cells combined with Atractylodes macrocephala polysaccharide attenuate ulcerative colitis. Bioengineered. 2022 Jan;13(1):824-833.(山东中医药大学)

9. Zhang X, et al. Effects Of Dietary Selenium On Immune Function Of Spleen In Mice. Journal of Functional Foods.2022 Jan;1(89):1676.(贵州医科大学)

10. Zhang Y, et al. The Potential Role of Serum IGF-1 and Leptin as Biomarkers: Towards Screening for and Diagnosing Postmenopausal Osteoporosis. J Inflamm Res. 2022 Jan 22;15:533-543.(南京中医药大学)

11. Du X, et al. The System Research of the Molecular Mechanism of Quyushengxin Capsule in the Treatment of Osteonecrosis of the Femoral Head. Evid Based Complement Alternat Med. 2022 Jan 11;2022:2968075.(陕西省中医药研究院)

12. Hu Z, et al. Single-Cell Transcriptomics Reveals Novel Role of Microglia in Fibrovascular Membrane of Proliferative Diabetic Retinopathy. Diabetes. 2022 Apr 1;71(4):762-773.(南京医科大学第一附属医院)

13. Hu T, et al. Liu Q, Chen F, Lei P. Inhibition of Exosome Release Alleviates Cognitive Impairment After Repetitive Mild Traumatic Brain Injury. Front Cell Neurosci. 2022 Jan 27;16:832140.(天津医科大学总医院)

14. Yang HL, et al. A defective lysophosphatidic acid-autophagy axis increases miscarriage risk by restricting decidual macrophage residence. Autophagy. 2022 Feb 27:1-22.(复旦大学附属妇产科医院)

15. Sun H, et al. Vitreous Inflammatory Cytokines and Chemokines, Not Altered After Preoperative Adjunctive Conbercept Injection, but Associated With Early Postoperative Macular Edema in Patients With Proliferative Diabetic Retinopathy. Front Physiol. 2022 Mar 3;13:846003.(南京医科大学第一附属医院)

16. Yin H, et al. Fusobacterium nucleatum promotes liver metastasis in colorectal cancer by regulating the hepatic immune niche and altering gut microbiota. Aging (Albany NY). 2022 Feb 25;14(4):1941-1958. doi: 10.18632/aging.203914.(华中科技大学附属同济医院)

17. Gao C, et al. Status of higher TGF-β1 and TGF-β2 levels in the aqueous humour of patients with diabetes and cataracts. BMC Ophthalmol. 2022 Apr 5;22(1):156.(复旦大学医学院)

18. Cao Y, et al. CD11c+ B Cells Participate in the Pathogenesis of Graves' Disease by Secreting Thyroid Autoantibodies and Cytokines. Front Immunol. 2022 Mar 21;13:836347.(北京大学第一医院)

19. Zhang Q, et al. Cardiovascular effects of traffic-related air pollution: A multi-omics analysis from a randomized, crossover trial. J Hazard Mater. 2022 Apr 29;435:129031.(复旦大学)

20. Zhang L, et al. Acute Myeloid Leukemia Cells Educate Mesenchymal Stromal Cells toward an Adipogenic Differentiation Propensity with Leukemia Promotion Capabilities. Adv Sci (Weinh). 2022 Mar 20:e2105811.(浙江大学医学院)

21. Xia C, et al. Autophagy and Exosome Coordinately Enhance Macrophage M1 Polarization and Recruitment in Influenza A Virus Infection. Front Immunol. 2022 Mar 17;13:722053.(复旦大学药学院)

22. Peng S, et al. Metabolomics reveals that CAF-derived lipids promote colorectal cancer peritoneal metastasis by enhancing membrane fluidity. Int J Biol Sci. 2022 Feb 21;18(5):1912-1932.(中山大学附属第六医院)

23. Fu Y, et al. Loss of neurodevelopmental-associated miR-592 impairs neurogenesis and causes social interaction deficits. Cell Death Dis. 2022 Apr 1;13(4):292.(同济大学医学院)

24. Jiang X, et al. EIF4A3-Induced circARHGAP29 Promotes Aerobic Glycolysis in Docetaxel-Resistant Prostate Cancer through IGF2BP2/c-Myc/LDHA Signaling. Cancer Res. 2022 Mar 1;82(5):831-845.(天津医科大学第二医院)

25. Ren QN, et al. Phosphorylation of androgen receptor by mTORC1 promotes liver steatosis and tumorigenesis. Hepatology. 2022 May;75(5):1123-1138.(中山大学附属肿瘤中心)

26. Du X, et al. Dynamic molecular choreography induced by traffic exposure: A randomized, crossover trial using multi-omics profiling. J Hazard Mater. 2022 Feb 15;424(Pt A):127359.(复旦大学公卫学院)

27. Peng Y, et al. JAM2 predicts a good prognosis and inhibits invasion and migration by suppressing EMT pathway in breast cancer. Int Immunopharmacol. 2022 Feb;103:108430.(重庆医科大学)

28. Jiang W, et al. PGE2 activates EP4 in subchondral bone osteoclasts to regulate osteoarthritis. Bone Res. 2022 Mar 9;10(1):27.(华东师大)

29. Zhou J, et al. The Expression of Cytokine Profiles and Related Receptors in Idiopathic Inflammatory Myopathies. Front Pharmacol. 2022 Apr 20;13:852055.(中南大学附属湘雅医院)

30. Huang T, et al. Regenerating Myofiber Directs Tregs and Th17 Responses in Inflamed Muscle through the Intrinsic TGF-β Signaling Mediated IL-6 Production. Am J Physiol Endocrinol Metab. 2022 May 9.(南方医科大学)

31. Yin S, et al. MS: Wip1 suppresses angiogenesis through the STAT3-VEGF signalling pathway in serous ovarian cancer. J Ovarian Res. 2022 May 10;15(1):56.(复旦大学中山医院)

32. Lv X, et al. IMB5036, a novel pyridazinone compound, inhibits hepatocellular carcinoma growth and metastasis. Invest New Drugs. 2022 Jun;40(3):487-496.(山西医科大学)

2021年:

1. Gu Y, et al. ABHD5 inhibits YAP-induced c-Met overexpression and colon cancer cell stemness via suppressing YAP methylation. Nat Commun. 2021 Nov 18;12(1):6711.(陆军军医大学西南医院)
 
2. Xu YN, et al. E17241 as a Novel ABCA1 (ATP-Binding Cassette Transporter A1) Upregulator Ameliorates Atherosclerosis in Mice. Arterioscler Thromb Vasc Biol. 2021 Jun;41(6):e284-e298.(中国医学科学院医药生物技术研究所)

3. Zhang P, et al. Bruceine A induces cell growth inhibition and apoptosis through PFKFB4/GSK3β signaling in pancreatic cancer. Pharmacol Res. 2021 Jul;169:105658.(南京中医药大学)

4. Zheng Y, et al. Regulation of decorin by ursolic acid protects against non-alcoholic steatohepatitis. Biomed Pharmacother. 2021 Nov;143:112166.(广州中医药大学第一附属医院)

5. Liang Y, et al. Rapamycin antagonizes cadmium-induced breast cancer cell proliferation and metastasis through directly modulating ACSS2. Ecotoxicol Environ Saf. 2021 Aug 16;224:112626.(第三军医大学)

6. Zhao T, et al. QPCT regulation by CTCF leads to sunitinib resistance in renal cell carcinoma by promoting angiogenesis. Int J Oncol. 2021 Jul;59(1):48. doi: 10.3892/ijo.2021.5228.(上海长征医院)

7. Wang CL, et al. Long non-coding RNA ARHGAP5-AS1 inhibits migration of breast cancer cell via stabilizing SMAD7 protein. Breast Cancer Res Treat. 2021 Oct;189(3):607-619.(上海交通大学医学院)

8. Chen W, et al. The Neurogenic Compound P7C3 Regulates the Aerobic Glycolysis by Targeting Phosphoglycerate Kinase 1 in Glioma. Front Oncol. 2021 Jun 18;11:644492.(解放军第七医学中心)

9. Wu Y, et al. Renalase improves pressure overload-induced heart failure in rats by regulating extracellular signal-regulated protein kinase 1/2 signaling. Hypertens Res. 2021 May;44(5):481-488.(中南大学湘雅医院)

10. Lin YX, et al. Reactivation of the tumor suppressor PTEN by mRNA nanoparticles enhances antitumor immunity in preclinical models. Sci Transl Med. 2021 Jun 23;13(599):eaba9772.(国家纳米科学中心)

11. Fu L, et al. Tetrahedral framework nucleic acids promote the biological functions and related mechanism of synovium-derived mesenchymal stem cells and show improved articular cartilage regeneration activity in situ. Bioact Mater. 2021 Jul 27;9:411-427.(中国人民解放军总医院骨科研究所)

12. Li H, et al. Li W, He Z, Zhang Q, Huang H, Lin J, Chen Y, Xing D, Du Y, Lin J. Targeted cell therapy for partial-thickness cartilage defects using membrane modified mesenchymal stem cells by transglutaminase 2. Biomaterials. 2021 Aug;275:120994.(北京大学人民医院)

13. Long H, et al. Progesterone affects clinic oocyte yields by coordinating with follicle stimulating hormone via PI3K/AKT and MAPK pathways. J Adv Res. 2021 Mar 2;33:189-199.(上海交通大学第九人民医院)

14. Huang T, et al. Rab1A promotes IL-4R/JAK1/STAT6-dependent metastasis and determines JAK1 inhibitor sensitivity in non-small cell lung cancer. Cancer Lett. 2021 Dec 28;523:182-194.(上海交通大学第九人民医院)

15. Zhao Q, et al. CXCL13 promotes intestinal tumorigenesis through the activation of epithelial AKT signaling. Cancer Lett. 2021 Jul 28;511:1-14.(湖北大学医学院)

16. Lv X, et al. Activation of PKM2 metabolically controls fulminant liver injury via restoration of pyruvate and reactivation of CDK1. Pharmacol Res. 2021 Oct;172:105838.(重庆医科大学)

17. Li J, et al. Transcriptomic Profiling Reveals a Role for TREM-1 Activation in Enterovirus D68 Infection-Induced Proinflammatory Responses. Front Immunol. 2021 Nov 23;12:749618.(天津大学)

18. Chen C, et al. 1800 MHz Radiofrequency Electromagnetic Field Impairs Neurite Outgrowth Through Inhibiting EPHA5 Signaling. Front Cell Dev Biol. 2021 Apr 12;9:657623.(第三军医大学)

19. Yang X, et al. High Expression of Cancer-IgG Is Associated With Poor Prognosis and Radioresistance via PI3K/AKT/DNA-PKcs Pathway Regulation in Lung Adenocarcinoma. Front Oncol. 2021 Jun 2;11:675397.(北京大学中日友好医院)

20. Liu L, et al. CD155 Promotes the Progression of Cervical Cancer Cells Through AKT/mTOR and NF-κB Pathways. Front Oncol. 2021 Jun 7;11:655302.(山东大学)

21. Yang S, et al. Zeylenone synergizes with cisplatin in osteosarcoma by enhancing DNA damage, apoptosis, and necrosis via the Hsp90/AKT/GSK3β and Fanconi anaemia pathway. Phytother Res. 2021 Oct;35(10):5899-5918.(中国医学科学院)

22. Wang W, et al. Phosphoproteomic Profiling of Rat's Dorsal Root Ganglia Reveals mTOR as a Potential Target in Bone Cancer Pain and Electro-Acupuncture's Analgesia. Front Pharmacol. 2021 Apr 29;12:593043.(浙江中医药大学)

23. Jia S, et al. Dissecting the novel mechanism of reduning injection in treating Coronavirus Disease 2019 (COVID-19) based on network pharmacology and experimental verification. J Ethnopharmacol. 2021 Jun 12;273:113871.(中药制药工艺新技术国家重点实验室)

24. Zhu D, et al. Downregulation of aromatase plays a dual role in preeclampsia. Mol Hum Reprod. 2021 Mar 24;27(4):gaab013.(第四军医大学)

25. Wei Q, et al. Proinflammatory and angiogenesis-related cytokines in vitreous samples of highly myopic patients. Cytokine. 2021 Jan;137:155308.(复旦大学上海医学院眼耳鼻喉科医院)

26. Tian G, et al. Cell-free decellularized cartilage extracellular matrix scaffolds combined with interleukin 4 promote osteochondral repair through immunomodulatory macrophages: In vitro and in vivo preclinical study. Acta Biomater. 2021 Jun;127:131-145.(中国人民解放军总医院骨科研究所)

27. Zhao S, et al. An Immunological Perspective: What Happened to Pregnant Women After Recovering From COVID-19? Front Immunol. 2021 Feb 3;12:631044.(华中科技大学同济医学院)

28. Li Z, et al. Allergen-Specific Treg Cells Upregulated by Lung-Stage S. japonicum Infection Alleviates Allergic Airway Inflammation. Front Cell Dev Biol. 2021 Jun 8;9:678377.(中国疾病预防控制中心寄生虫病研究所)

29. Fang L, et al. LAMC1 upregulation via TGFβ induces inflammatory cancer-associated fibroblasts in esophageal squamous cell carcinoma via NF-κB-CXCL1-STAT3. Mol Oncol. 2021 Nov;15(11):3125-3146.(中国科学院肿瘤医院)

30. Liu Q, et al. Ramulus Mori (Sangzhi) Alkaloids (SZ-A) Ameliorate Glucose Metabolism Accompanied by the Modulation of Gut Microbiota and Ileal Inflammatory Damage in Type 2 Diabetic KKAy Mice. Front Pharmacol. 2021 Apr 15;12:642400.(中国医学科学院北京协和医学院药物研究所)

31. Ren M, et al. Allergic Asthma-Induced Cognitive Impairment is Alleviated by Dexamethasone. Front Pharmacol. 2021 Jun 23;12:680815.(重庆医科大学)

32. Fang L, et al. PLAU directs conversion of fibroblasts to inflammatory cancer-associated fibroblasts, promoting esophageal squamous cell carcinoma progression via uPAR/Akt/NF-κB/IL8 pathway. Cell Death Discov. 2021 Feb 11;7(1):32.(中国医学科学院北京协和医学院国家癌症中心)

33. Liu Q, et al. CGRP-Mediated Prolactin Upregulation: a Possible Pathomechanism in IgG4-Related Disease. Inflammation. 2021 Apr;44(2):536-548.(福建医科大学附属第一医院)

34. Jiang H, et al. Is there a relationship between plasma, cytokine concentrations, and the subsequent risk of postpartum hemorrhage? Am J Obstet Gynecol. 2021 Dec 15:S0002-9378(21)02681-8.(北医三院妇产科)

35. Zhao S, et al. Changes of Dry Eye Related Markers and Tear Inflammatory Cytokines After Upper Blepharoplasty. Front Med (Lausanne). 2021 Dec 9;8:763611.(复旦大学胸科医院)

36. Yu H, et al. Human Adipose Mesenchymal Stem Cell-derived Exosomes Protect Mice from DSS-Induced Inflammatory Bowel Disease by Promoting Intestinal-stem-cell and Epithelial Regeneration. Aging Dis. 2021 Sep 1;12(6):1423-1437.(北京医科大学)

37. Hu Z, et al. Monitoring intraocular proangiogenic and profibrotic cytokines within 7 days after adjunctive anti-vascular endothelial growth factor therapy for proliferative diabetic retinopathy. Acta Ophthalmol. 2022 May;100(3):e726-e736.(南京医科大学)

38. Chu F, et al. Gut Microbial Dysbiosis and Changes in Fecal Metabolic Phenotype in Precancerous Lesions of Gastric Cancer Induced With N-Methyl-N'-Nitro-N-Nitrosoguanidine, Sodium Salicylate, Ranitidine, and Irregular Diet. Front Physiol. 2021 Nov 4;12:733979.(北京中医药大学)

39. Li F, et al. Hepatic lysosomal acid lipase drives the autophagy-lysosomal response and alleviates cholesterol metabolic disorder in ApoE deficient mice. Biochim Biophys Acta Mol Cell Biol Lipids. 2021 Dec;1866(12):159027.(武汉大学基础医学院)

40. Man QW, et al. Single-Cell RNA Sequencing Reveals CXCLs Enriched Fibroblasts Within Odontogenic Keratocysts. J Inflamm Res. 2021 Dec 24;14:7359-7369.(武汉大学)

41. Yu J, et al. Quyu Shengxin capsule (QSC) inhibits Ang-II-induced abnormal proliferation of VSMCs by down-regulating TGF-β, VEGF, mTOR and JAK-STAT pathways. J Ethnopharmacol. 2021 Jul 15;275:114112.(陕西中医药大学)

42. Pei X, et al. Targeting HMGB1 inhibits T-2 toxin-induced neurotoxicity via regulation of oxidative stress, neuroinflammation and neuronal apoptosis. Food Chem Toxicol. 2021 May;151:112134.(中国农业大学)

43. Feng Z, et al. Neutrophil Extracellular Traps Exacerbate Secondary Injury via Promoting Neuroinflammation and Blood-Spinal Cord Barrier Disruption in Spinal Cord Injury. Front Immunol. 2021 Aug 11;12:698249.(第三军医大学)

44. Li Q, et al. Propionibacterium acnes overabundance in gastric cancer promote M2 polarization of macrophages via a TLR4/PI3K/Akt signaling. Gastric Cancer. 2021 Nov;24(6):1242-1253.(武汉大学人民医院)

45. Wei G, et al. Polydopamine-Decorated Microcomposites Promote Functional Recovery of an Injured Spinal Cord by Inhibiting Neuroinflammation. ACS Appl Mater Interfaces. 2021 Oct 13;13(40):47341-47353.(南京医科大学)

46. Xu J, et al. TRPV2-spike protein interaction mediates the entry of SARS-CoV-2 into macrophages in febrile conditions. Theranostics. 2021 May 25;11(15):7379-7390.(宁夏大学)

47. Shi J, et al. IL-10 alleviates lipopolysaccharide-induced skin scarring via IL-10R/STAT3 axis regulating TLR4/NF-κB pathway in dermal fibroblasts. J Cell Mol Med. 2021 Feb;25(3):1554-1567.(第四军医大学西京医院)

48. Zhi H, et al. Restoring perturbed oxylipins with Danqi Tongmai Tablet attenuates acute myocardial infarction. Phytomedicine. 2021 Sep;90:153616.(中国科学院药物研究所)

49. Song Z, et al. Microarray microRNA profiling of urinary exosomes in a 5XFAD mouse model of Alzheimer's disease. Animal Model Exp Med. 2021 Jun 9;4(3):233-242.(中国医学科学院实验动物研究所)

50. Sun X, et al. Small extracellular vesicles secreted by vaginal fibroblasts exert inhibitory effect in female stress urinary incontinence through regulating the function of fibroblasts. PLoS One. 2021 Apr 9;16(4):e0249977.(浙大妇产科医院)

51. Dong Z, et al. Profiling of Serum Exosome MiRNA Reveals the Potential of a MiRNA Panel as Diagnostic Biomarker for Alzheimer's Disease. Mol Neurobiol. 2021 Jul;58(7):3084-3094.(上海第六人民医院金山分院)

52. Yang Q, et al. Novel Biomarkers of Dynamic Blood PD-L1 Expression for Immune Checkpoint Inhibitors in Advanced Non-Small-Cell Lung Cancer Patients. Front Immunol. 2021 Apr 16;12:665133.(陆军医科大学新桥医院)
 
53. Luo L, et al. Cartilage endplate stem cells inhibit intervertebral disc degeneration by releasing exosomes to nucleus pulposus cells to activate Akt/autophagy. Stem Cells. 2021 Apr;39(4):467-481.(第三军医大学)

54. Liu H, et al. Investigating the growth performance, meat quality, immune function and proteomic profiles of plasmal exosomes in Lactobacillus plantarum-treated broilers with immunological stress. Food Funct. 2021 Nov 29;12(23):11790-11807.(青岛农业大学)

55. Feng W, et al. MiR-6924-5p-rich exosomes derived from genetically modified Scleraxis-overexpressing PDGFRα(+) BMMSCs as novel nanotherapeutics for treating osteolysis during tendon-bone healing and improving healing strength. Biomaterials. 2021 Dec;279:121242.(第三军医大学一附院)

56. Li SJ, et al. A Next-Generation Sequencing of Plasma Exosome-Derived microRNAs and Target Gene Analysis with a Microarray Database of Thermally Injured Skins: Identification of Blood-to-Tissue Interactions at Early Burn Stage. J Inflamm Res. 2021 Dec 10;14:6783-6798.(安徽医科大学第一附属医院)

57. Li Q, et al. Exosomal MicroRNA-21 Promotes Keloid Fibroblast Proliferation and Collagen Production by Inhibiting Smad7. J Burn Care Res. 2021 Nov 24;42(6):1266-1274.(四川大学华西医院)

58. Wang X, et al. Extracellular Vesicles Inhibit Proliferation and Invasion of Ovarian Endometrial Stromal Cells and Their Expression of SF-1, ERβ, and Aromatase. Front Endocrinol (Lausanne). 2021 Aug 31;12:666195.(北京大学第一附属医院)

59. Song WP, et al. Proteomic analysis and miRNA profiling of human testicular endothelial cell-derived exosomes: the potential effects on spermatogenesis. Asian J Androl. 2021 Dec 17.(北京大学第一附属医院)

60. Li Y, et al. A Novel Urine Exosomal lncRNA Assay to Improve the Detection of Prostate Cancer at Initial Biopsy: A Retrospective Multicenter Diagnostic Feasibility Study. Cancers (Basel). 2021 Aug 13;13(16):4075.(长海医院)

61. Zhang Z, et al. Micro/nano-textured hierarchical titanium topography promotes exosome biogenesis and secretion to improve osseointegration. J Nanobiotechnology. 2021 Mar 19;19(1):78.(中山大学)

62. Luo L, et al. Injectable cartilage matrix hydrogel loaded with cartilage endplate stem cells engineered to release exosomes for non-invasive treatment of intervertebral disc degeneration. Bioact Mater. 2021 Dec 21;15:29-43.(第三军医大学)

63. Chen L, et al. Bacterial cytoplasmic membranes synergistically enhance the antitumor activity of autologous cancer vaccines. Sci Transl Med. 2021 Jul 7;13(601):eabc2816.(国家纳米科学中心)

64. Zhu C, et al. UPF1 promotes chemoresistance to oxaliplatin through regulation of TOP2A activity and maintenance of stemness in colorectal cancer. Cell Death Dis. 2021 May 21;12(6):519.(复旦大学附属肿瘤医院)

65. Tong Y, et al. Radiogenomic Analysis of Papillary Thyroid Carcinoma for Prediction of Cervical Lymph Node Metastasis: A Preliminary Study. Front Oncol. 2021 Jun 29;11:682998.(复旦大学附属肿瘤医院)

66. Guo Y, et al. miR-29a/b1 Regulates the Luteinizing Hormone Secretion and Affects Mouse Ovulation. Front Endocrinol (Lausanne). 2021 May 31;12:636220.(上海交通大学医学院附属瑞金医院)

67. Liu H, et al. Investigating the growth performance, meat quality, immune function and proteomic profiles of plasmal exosomes in Lactobacillus plantarum-treated broilers with immunological stress. Food Funct. 2021 Nov 29;12(23):11790-11807.(青岛农业大学)

68. Liu Q, et al. CGRP-Mediated Prolactin Upregulation: a Possible Pathomechanism in IgG4-Related Disease. Inflammation. 2021 Apr;44(2):536-548.(福建医科大学附属第一医院)

69. Lu H, et al. Rapamycin prevents spontaneous abortion by triggering decidual stromal cell autophagy-mediated NK cell residence. Autophagy. 2021 Sep;17(9):2511-2527.(复旦大学上海医学院)

70. Ding J, et al. M2 macrophage-derived G-CSF promotes trophoblasts EMT, invasion and migration via activating PI3K/Akt/Erk1/2 pathway to mediate normal pregnancy. J Cell Mol Med. 2021 Feb;25(4):2136-2147.(武汉大学人民医院生殖医学中心)

71. Wang Q, et al. The Rs12569232 SNP Association with Vogt-Koyanagi-Harada Disease and Behcet's Disease is Probably Mediated by Regulation of Linc00467 Expression. Ocul Immunol Inflamm. 2021 Nov 17;29(7-8):1464-1470.(重庆医科大学第一附属医院)

72. Yang L, et al. Acetyl-bufalin shows potent efficacy against non-small-cell lung cancer by targeting the CDK9/STAT3 signalling pathway. Br J Cancer. 2021 Feb;124(3):645-657.(温州医科大学)

73. Zhu R, et al. Mesenchymal stem cell treatment improves outcome of COVID-19 patients via multiple immunomodulatory mechanisms. Cell Res. 2021 Dec;31(12):1244-1262.(中国医学科学院)

2020年:

1. Ye S, et al. Celastrol Attenuates Angiotensin II-Induced Cardiac Remodeling by Targeting STAT3. Circ Res. 2020 Apr 10;126(8):1007-1023.(温州医科大学)

2. Yu JJ, et al. TRIB3-EGFR interaction promotes lung cancer progression and defines a therapeutic target. Nat Commun. 2020 Jul 21;11(1):3660.(中国医学科学院药物研究所)

3. Chen X, et al. Celastrol induces ROS-mediated apoptosis via directly targeting peroxiredoxin-2 in gastric cancer cells. Theranostics. 2020 Aug 15;10(22):10290-10308.(温州医科大学)

4. Zhou Y, et al. PBX1 expression in uterine natural killer cells drives fetal growth. Sci Transl Med. 2020 Apr 1;12(537):eaax1798.(中国科学技术大学)

5. Chen WL, et al. GLUT5-mediated fructose utilization drives lung cancer growth by stimulating fatty acid synthesis and AMPK/mTORC1 signaling. JCI Insight. 2020 Feb 13;5(3):e131596.(上海中医药大学附属龙华医院)

6. Gan X, et al. Acidic Microenvironment Regulates the Severity of Hepatic Ischemia/Reperfusion Injury by Modulating the Generation and Function of Tregs via the PI3K-mTOR Pathway. Front Immunol. 2020 Jan 9;10:2945.(南京医科大学)

7. Cai J, et al. Non-metabolic role of UCK2 links EGFR-AKT pathway activation to metastasis enhancement in hepatocellular carcinoma. Oncogenesis. 2020 Dec 4;9(12):103.(上海交通大学医学院仁济医院)

8. Yan L, et al. Bioglass could increase cell membrane fluidity with ion products to develop its bioactivity. Cell Prolif. 2020 Nov;53(11):e12906.(上海交通大学生物医学工程学院)

9. Wan H, et al. 3,4,5-Tri-O-caffeoylquinic acid methyl ester isolated from Lonicera japonica Thunb. Flower buds facilitates hepatitis B virus replication in HepG2.2.15 cells. Food Chem Toxicol. 2020 Apr;138:111250.(暨南大学第二临床医学院)

10. Leng J, et al. Amelioration of non-alcoholic steatohepatitis by Qushi Huayu decoction is associated with inhibition of the intestinal mitogen-activated protein kinase pathway. Phytomedicine. 2020 Jan;66:153135.(上海中医药大学附属曙光医院)
 
11. Zhang X, et al. Mechanical stress regulates autophagic flux to affect apoptosis after spinal cord injury. J Cell Mol Med. 2020 Nov;24(21):12765-12776.(首都医科大学)

12. Fan D, et al. Deciphering Antitumor Mechanism of Pien Tze Huang in Mice of Hepatocellular Carcinoma Based on Proteomics. J Immunol Res. 2020 Dec 3;2020:4876251.(广州中医药大学第二临床医学院)

13. Fan Q, et al. Chip-based serum proteomics approach to reveal the potential protein markers in the sub-acute stroke patients receiving the treatment of Ginkgo Diterpene Lactone Meglumine Injection. J Ethnopharmacol. 2020 Oct 5;260:112964.(中国药科大学生命科学与技术学院)

14. Zhou DD, et al. Metallothionein-2 is associated with the amelioration of asthmatic pulmonary function by acupuncture through protein phosphorylation. Biomed Pharmacother. 2020 Mar;123:109785.(上海针研所)

15. Yang Y, et al. A novel di-peptide Met-Glu from collagen hydrolysates inhibits platelet aggregation and thrombus formation via regulation of Gq-mediated signaling. J Food Biochem. 2020 Sep;44(9):e13352.(中国农业大学食品科学与营养工程学院)

16. Wang J, et al. Tanshinone IIA protects mice against atherosclerotic injury by activating the TGF-β/PI3K/Akt/eNOS pathway. Coron Artery Dis. 2020 Jun;31(4):385-392.(辽宁中医药大学基础医学院)

17. Li H, et al. Salidroside improves high-fat diet-induced non-alcoholic steatohepatitis by regulating the gut microbiota-bile acid-farnesoid X receptor axis. Biomed Pharmacother. 2020 Apr;124:109915.(上海中医药大学附属曙光医院)

18. He M, et al. The potential markers involved in newly diagnosed graves' disease and the development of active graves' orbitopathy. Cytokine. 2020 Mar;127:154998.(西安交大一附院)

19. Liu C, et al. A riboflavin-ultraviolet light A-crosslinked decellularized heart valve for improved biomechanical properties, stability, and biocompatibility. Biomater Sci. 2020 May 6;8(9):2549-2563.(华中科技大学同济医学院)

20. Li Y, et al. Csf2 Attenuated Sepsis-Induced Acute Kidney Injury by Promoting Alternative Macrophage Transition. Front Immunol. 2020 Jul 7;11:1415.(武汉大学中南医院重症医学科)

21. Jia Z, et al. Hepatotoxicity assessment of Rhizoma Paridis in adult zebrafish through proteomes and metabolome. Biomed Pharmacother. 2020 Jan;121:109558. (复旦大学附属眼耳鼻喉科医院)

22. Diao S, et al. Immune cell infiltration and cytokine secretion analysis reveal a non-inflammatory microenvironment of medulloblastoma. Oncol Lett. 2020 Dec;20(6):397.(首都医科大学三博脑医院神经外科)

23. Lv X, et al. Maladjustment of β-CGRP/α-CGRP Regulation of AQP5 Promotes Transition of Alveolar Epithelial Cell Apoptosis to Pulmonary Fibrosis. J Interferon Cytokine Res. 2020 Aug;40(8):377-388.(福建医科大学第一附属医院)

24. He Y, et al. Major depression accompanied with inflammation and multiple cytokines alterations: Evidences from clinical patients to macaca fascicularis and LPS-induced depressive mice model. J Affect Disord. 2020 Jun 15;271:262-271.(重庆医科大学)

25. Fan Q, et al. Chip-based serum proteomics approach to reveal the potential protein markers in the sub-acute stroke patients receiving the treatment of Ginkgo Diterpene Lactone Meglumine Injection. J Ethnopharmacol. 2020 Oct 5;260:112964.(中国药科大学生命科学与技术学院)

26. Zhu X, et al. Profiling and Bioinformatic Analysis of Differentially Expressed Cytokines in Aqueous Humor of High Myopic Eyes - Clues for Anti-VEGF Injections. Curr Eye Res. 2020 Jan;45(1):97-103.(复旦大学附属眼耳鼻喉科医院)

27. Bian X, et al. Regenerative and protective effects of dMSC-sEVs on high-glucose-induced senescent fibroblasts by suppressing RAGE pathway and activating Smad pathway. Stem Cell Res Ther. 2020 Apr 29;11(1):166.(中国人民解放军总医院第四医学中心)

28. Ren Y, et al. Human amniotic epithelial cells ameliorate kidney damage in ischemia-reperfusion mouse model of acute kidney injury. Stem Cell Res Ther. 2020 Sep 23;11(1):410.(北京大学附属第一医院)

29. Shi Y, et al. Exosomes Derived from Bone Marrow Stromal Cells (BMSCs) Enhance Tendon-Bone Healing by Regulating Macrophage Polarization. Med Sci Monit. 2020 May 5;26:e923328.(陆军军医大学第一附属医院)

30. Bai X, et al. Extracellular Vesicles From Adipose Tissue-Derived Stem Cells Affect Notch-miR148a-3p Axis to Regulate Polarization of Macrophages and Alleviate Sepsis in Mice. Front Immunol. 2020 Jul 3;11:1391.(空军军医大学)

31. Yang C, et al. Highly-expressed micoRNA-21 in adipose derived stem cell exosomes can enhance the migration and proliferation of the HaCaT cells by increasing the MMP-9 expression through the PI3K/AKT pathway. Arch Biochem Biophys. 2020 Mar 15;681:108259.(空军军医大学第一附属医院)

32. Wang T, et al. MSC-derived exosomes protect against oxidative stress-induced skin injury via adaptive regulation of the NRF2 defense system. Biomaterials. 2020 Oct;257:120264.(西安市中心医院)

33. Chen CW, et al. Long Noncoding RNA MRPL23-AS1 Promotes Adenoid Cystic Carcinoma Lung Metastasis. Cancer Res. 2020 Jun 1;80(11):2273-2285.(北京大学口腔医学院)

34. Peng C, et al. Isolation of extracellular vesicle with different precipitation-based methods exerts a tremendous impact on the biomarker analysis for clinical plasma samples. Cancer Biomark. 2020;29(3):373-385.(上海交大医学院附属瑞金医院)

35. Gao G, et al. Glutaminase 1 Regulates Neuroinflammation After Cerebral Ischemia Through Enhancing Microglial Activation and Pro-Inflammatory Exosome Release. Front Immunol. 2020 Feb 7;11:161. (同济大学)

36. Song Z, et al. Comprehensive Proteomic Profiling of Urinary Exosomes and Identification of Potential Non-invasive Early Biomarkers of Alzheimer's Disease in 5XFAD Mouse Model. Front Genet. 2020 Nov 5;11:565479.(中国医学科学院实验动物研究所)
 
37. Si J, et al. Hematopoietic Progenitor Kinase1 (HPK1) Mediates T Cell Dysfunction and Is a Druggable Target for T Cell-Based Immunotherapies. Cancer Cell. 2020 Oct 12;38(4):551-566.e11.(清华大学-广州中山医院)

38. Wang Y, et al. Integrin β1D Deficiency-Mediated RyR2 Dysfunction Contributes to Catecholamine-Sensitive Ventricular Tachycardia in Arrhythmogenic Right Ventricular Cardiomyopathy. Circulation. 2020 May 5;141(18):1477-1493.(中国医学科学院阜外医院)

39. Jia Z, et al. Hepatotoxicity assessment of Rhizoma Paridis in adult zebrafish through proteomes and metabolome. Biomed Pharmacother. 2020 Jan;121:109558.(北京中医药大学)

40. Li M, et al. Metabolic Disorder of Extracellular Matrix Mediated by Decorin Upregulation Is Associated With Brain Arteriovenous Malformation Diffuseness. Front Aging Neurosci. 2020 Dec 7;12:584839.(首都医科大学附属北京天坛医院)

41. Zhao C, et al. Integrative analysis of proteomic and metabonomics data for identification of pathways related to Rhizoma Paridis-induced hepatotoxicity. Sci Rep. 2020 Apr 16;10(1):6540.(北京中医药大学)

42. Yu TY, et al. Proteomic study of hypothalamus in pigs exposed to heat stress. BMC Vet Res. 2020 Aug 12;16(1):286. (广东海洋大学兽医系)

43. Jiang Y, et al. Upregulation of AKR1C1 in mesenchymal stromal cells promotes the survival of acute myeloid leukaemia cells. Br J Haematol. 2020 May;189(4):694-706.(中国医学科学院血液病研究所)

44. Chen Y, et al. Higher TGF-β2 Level in the Aqueous Humor of the Second Eye Versus the First Eye in the Course of Sequential Cataract Surgery. Ocul Immunol Inflamm. 2020 Apr 2;28(3):439-445.(重庆医科大学)

45. Liu W, et al. Cisplatin-stimulated macrophages promote ovarian cancer migration via the CCL20-CCR6 axis. Cancer Lett. 2020 Mar 1;472:59-69.(上海交通大学附属仁济医院妇产科)

46. Ye Y, et al. Polygalasaponin F treats mice with pneumonia induced by influenza virus. Inflammopharmacology. 2020 Feb;28(1):299-310.(广州中医药大学)

47. He D, et al. Gut stem cell aging is driven by mTORC1 via a p38 MAPK-p53 pathway. Nat Commun. 2020 Jan 2;11(1):37.(上海交通大学)

48. Yu B, et al. A Novel LncRNA, AC091729.7 Promotes Sinonasal Squamous Cell Carcinomas Proliferation and Invasion Through Binding SRSF2. Front Oncol. 2020 Jan 24;9:1575.(哈尔滨医科大学附属第二医院)

49. Geng N, et al. A PAK5-DNPEP-USP4 axis dictates breast cancer growth and metastasis. Int J Cancer. 2020 Feb 15;146(4):1139-1151.(中国医科大学)

50. Li J, et al. Unmethylated CpG motif-containing genomic DNA fragment of Bacillus calmette-guerin promotes macrophage functions through TLR9-mediated activation of NF-κB and MAPKs signaling pathways. Innate Immun. 2020 Apr;26(3):183-203.(中国食品药品检定研究院)

2019年:

1. Xu QG, et al. A novel HBx genotype serves as a preoperative predictor and fails to activate the JAK1/STATs pathway in hepatocellular carcinoma. J Hepatol. 2019 May;70(5):904-917.(东方肝胆外科医院)

2. Zhao T, et al. DNA methylation-regulated QPCT promotes sunitinib resistance by increasing HRAS stability in renal cell carcinoma. Theranostics. 2019 Aug 14;9(21):6175-6190.(长征医院泌尿外科)

3. Kang CL, et al. LncRNA AY promotes hepatocellular carcinoma metastasis by stimulating ITGAV transcription. Theranostics. 2019 Jun 9;9(15):4421-4436.(复旦大学基础医学院)

4. Chen XJ, et al. Homoharringtonine deregulates MYC transcriptional expression by directly binding NF-κB repressing factor. Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):2220-2225.(上海交通大学附属瑞金医院)

5. Zhao T, et al. ANGPTL3 inhibits renal cell carcinoma metastasis by inhibiting VASP phosphorylation. Biochem Biophys Res Commun. 2019 Aug 27;516(3):880-887.(长征医院泌尿外科)

6. Zhou X, et al. Splicing factor SRSF1 promotes gliomagenesis via oncogenic splice-switching of MYO1B. J Clin Invest. 2019 Feb 1;129(2):676-693.(天津医科大学总医院)

7. Gu C, et al. Discovery of the Oncogenic Parp1, a Target of bcr-abl and a Potential Therapeutic, in mir-181a/PPFIA1 Signaling Pathway. Mol Ther Nucleic Acids. 2019 Jun 7;16:1-14.(暨南大学)

8. Zeng Q, et al. Inhibition of ZIP4 reverses epithelial-to-mesenchymal transition and enhances the radiosensitivity in human nasopharyngeal carcinoma cells. Cell Death Dis. 2019 Aug 5;10(8):588.(四川大学)

9. Liu Q, et al. PRSS1 mutation: a possible pathomechanism of pancreatic carcinogenesis and pancreatic cancer. Mol Med. 2019 Sep 14;25(1):44.(福建医科大学)

10. Tian R, et al. Fibroblast growth factor-5 promotes spermatogonial stem cell proliferation via ERK and AKT activation. Stem Cell Res Ther. 2019 Jan 22;10(1):40.(上海总医院生殖医学重点实验室)

11. Shi Y, et al. RhTyrRS (Y341A), a novel human tyrosyl-tRNA synthetase mutant, stimulates thrombopoiesis through activation of the VEGF-R II/NF-κB pathway. Biochem Pharmacol. 2019 Nov;169:113634.(复旦大学生物医学研究所)

12. Fang B, et al. The effects of mechanical stretch on the biological characteristics of human adipose-derived stem cells. J Cell Mol Med. 2019 Jun;23(6):4244-4255.(上海交通大学医学院附属第九人民医院)

13. Lai Z, et al. Circular RNA 0047905 acts as a sponge for microRNA4516 and microRNA1227-5p, initiating gastric cancer progression. Cell Cycle. 2019 Jul;18(14):1560-1572.(山西省医学科学院山西大邑医院)

14. Guo P, et al. Cytosolic phospholipase A2α modulates cell-matrix adhesion via the FAK/paxillin pathway in hepatocellular carcinoma. Cancer Biol Med. 2019 May;16(2):377-390.(天津医科大学肿瘤医院)

15. Xia Z, et al. Cadherin Related Family Member 2 Acts As A Tumor Suppressor By Inactivating AKT In Human Hepatocellular Carcinoma. J Cancer. 2019 Jan 29;10(4):864-873.(第二军医大学药学院)

16. Gu X, et al. MAGEC2 Correlates With Unfavorable Prognosis And Promotes Tumor Development In HCC Via Epithelial-Mesenchymal Transition. Onco Targets Ther. 2019 Sep 24;12:7843-7855.(东南大学)

17. He M, et al. Golgi Phosphoprotein 3 Promotes Malignant Phenotypes via FAK/Raf/MEK and Wnt/β-Catenin Signaling Pathways in Human Renal Cell Carcinoma. J Biomed Nanotechnol. 2019 Aug 1;15(8):1812-1823.(中山大学一附院)

18. Huang Y, et al. Moxibustion Eases Chronic Inflammatory Visceral Pain In Rats Via MAPK Signaling Pathway In The Spinal Cord. J Pain Res. 2019 Nov 7;12:2999-3012.(上海中医药大学)

19. Mei J, et al. Nerve modulation therapy in gouty arthritis: targeting increased sFRP2 expression in dorsal root ganglion regulates macrophage polarization and alleviates endothelial damage. Theranostics. 2019 May 31;9(13):3707-3722.(上海交通大学医学院附属九院)

20. Wu L, et al. Berberine promotes the recruitment and activation of brown adipose tissue in mice and humans. Cell Death Dis. 2019 Jun 13;10(6):468.(上海药物所)

21. Liang Y, et al. Superagonistic CD28 protects against renal ischemia injury induced fibrosis through a regulatory T-cell expansion dependent mechanism. BMC Nephrol. 2019 Nov 9;20(1):407.(中山医院肾内科)

22. Chang RQ, et al. Decidual RANKL/RANK interaction promotes the residence and polarization of TGF-β1-producing regulatory γδ T cells. Cell Death Dis. 2019 Feb 8;10(2):113.(复旦大学附属妇产科医院)

23. Zhang X, et al. Selective Serotonin Reuptake Inhibitors Aggravate Depression-Associated Dry Eye Via Activating the NF-κB Pathway. Invest Ophthalmol Vis Sci. 2019 Jan 2;60(1):407-419.(复旦大学附属眼耳鼻喉科医院)

24. Meng D, et al. Effects of VEGFR1+ hematopoietic progenitor cells on pre-metastatic niche formation and in vivo metastasis of breast cancer cells. J Cancer Res Clin Oncol. 2019 Feb;145(2):411-427.(西安交通大学第一附属医院)

25. Qiao L, et al. microRNA-21-5p dysregulation in exosomes derived from heart failure patients impairs regenerative potential. J Clin Invest. 2019 Apr 29;129(6):2237-2250.(郑州大学)

26. Wang A, et al. Long noncoding RNA EGFR-AS1 promotes cell growth and metastasis via affecting HuR mediated mRNA stability of EGFR in renal cancer. Cell Death Dis. 2019 Feb 15;10(3):154.(第二军医大学)

27. Geranpayehvaghei M, et al. Targeting Delivery of Platelets Inhibitor to Prevent Tumor Metastasis. Bioconjug Chem. 2019 Sep 18;30(9):2349-2357.(国家纳米科学中心)

28. Zhao X, et al. lncRNA ZEB1-AS1 promotes migration and metastasis of bladder cancer cells by post-transcriptional activation of ZEB1. Int J Mol Med. 2019 Jul;44(1):196-206.(协和医院泌尿外科)

29. Ou J, et al. ABHD5 blunts the sensitivity of colorectal cancer to fluorouracil via promoting autophagic uracil yield. Nat Commun. 2019 Mar 6;10(1):1078.(陆军军医大学西南医院)

2018年:

1. Shen SM, et al. Nuclear PTEN safeguards pre-mRNA splicing to link Golgi apparatus for its tumor suppressive role. Nat Commun. 2018 Jun 19;9(1):2392.(上海交通大学医学院)

2. Wang Y, et al. HIC1 deletion promotes breast cancer progression by activating tumor cell/fibroblast crosstalk. J Clin Invest. 2018 Dec 3;128(12):5235-5250.(复旦上海癌症中心癌症研究所)

3. Qin M, et al. Circ-UBR5: An exonic circular RNA and novel small nuclear RNA involved in RNA splicing. Biochem Biophys Res Commun. 2018 Sep 5;503(2):1027-1034.(上海交大医学院)

4. Yin LM, et al. Transgelin-2 as a therapeutic target for asthmatic pulmonary resistance. Sci Transl Med. 2018 Feb 7;10(427):eaam8604.(上海岳阳医院针研所)

5. Liu D, et al. C/EBPβ enhances platinum resistance of ovarian cancer cells by reprogramming H3K79 methylation. Nat Commun. 2018 Apr 30;9(1):1739.(武汉同济医院)

6. Chen C, et al. Suppression of lung cancer progression by isoliquiritigenin through its metabolite 2, 4, 2', 4'-Tetrahydroxychalcone. J Exp Clin Cancer Res. 2018 Oct 3;37(1):243.(上海中医药大学中药复杂系统研究中心)

7. Du F, et al. DDIT4 promotes gastric cancer proliferation and tumorigenesis through the p53 and MAPK pathways. Cancer Commun (Lond). 2018 Jul 5;38(1):45.(西京医院)

8. Ge X, et al. Midostaurin potentiates rituximab antitumor activity in Burkitt's lymphoma by inducing apoptosis. Cell Death Dis. 2018 Dec 18;10(1):8.(复旦大学中山医院病理科)

9. Xu Y, et al. Sphingosine kinase 1 overexpression contributes to sunitinib resistance in clear cell renal cell carcinoma. Oncoimmunology. 2018 Sep 25;7(12):e1502130.(上海交通大学医学院仁济医院泌尿外科)

10. Hu C, et al. Complement Inhibitor CRIg/FH Ameliorates Renal Ischemia Reperfusion Injury via Activation of PI3K/AKT Signaling. J Immunol. 2018 Dec 15;201(12):3717-3730.(复旦大学中山医院泌尿外科)

11. Dai B, et al. HMQ-T-B10 induces human liver cell apoptosis by competitively targeting EphrinB2 and regulating its pathway. J Cell Mol Med. 2018 Nov;22(11):5231-5243.(西安交大)

12. Hu S, et al. The long noncoding RNA LOC105374325 causes podocyte injury in individuals with focal segmental glomerulosclerosis. J Biol Chem. 2018 Dec 28;293(52):20227-20239.(南京大学医学院)

13. Zhao Y, et al. Fingolimod targets cerebral endothelial activation to block leukocyte recruitment in the central nervous system. J Leukoc Biol. 2018 Jan;103(1):107-118.(南京医科大学)

14. Li Y, et al. Long non-coding RNA GPR65-1 is up-regulated in gastric cancer and promotes tumor growth through the PTEN-AKT-slug signaling pathway. Cell Cycle. 2018;17(6):759-765.(北大人民医院)

15. Lin J, et al. Characterizing the molecular mechanisms of acquired temozolomide resistance in the U251 glioblastoma cell line by protein microarray. Oncol Rep. 2018 May;39(5):2333-2341.(二军大)

16. Yang H, et al. Intracellular osteopontin negatively regulates toll-like receptor 4-mediated inflammatory response via regulating GSK3β and 4EBP1 phosphorylation. Cytokine. 2018 Aug;108:89-95.(上海儿童医学中心)

17. Gong X, et al. Expression of ILK in renal stroma is essential for multiple aspects of renal development. Am J Physiol Renal Physiol. 2018 Aug 1;315(2):F374-F385.(同济大学附属东方医院)

18. Tan H, et al. A Possible Role for Long Interspersed Nuclear Elements-1 (LINE-1) in Huntington's Disease Progression. Med Sci Monit. 2018 May 31;24:3644-3652.(华中科技大学附属同济医院)

19. Lin Y, et al. Serum IL-1ra, a novel biomarker predicting olanzapine-induced hypercholesterolemia and hyperleptinemia in schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Jun 8;84(Pt A):71-78.(上海市精神卫生中心)

20. Zhang J, et al. IL-17 Promotes Scar Formation by Inducing Macrophage Infiltration. Am J Pathol. 2018 Jul;188(7):1693-1702.(西京医院烧伤皮肤外科)

21. Wu QY, et al. CUEDC2, a novel interacting partner of the SOCS1 protein, plays important roles in the leukaemogenesis of acute myeloid leukaemia. Cell Death Dis. 2018 Jul 10;9(7):774.(徐州医科大学血液病研究所)

22. Goff DC, et al. Association of Hippocampal Atrophy With Duration of Untreated Psychosis and Molecular Biomarkers During Initial Antipsychotic Treatment of First-Episode Psychosis. JAMA Psychiatry. 2018 Apr 1;75(4):370-378.(上海市精神卫生中心)

23. Chen Z, et al. Dual effect of DLBCL-derived EXOs in lymphoma to improve DC vaccine efficacy in vitro while favor tumorgenesis in vivo. J Exp Clin Cancer Res. 2018 Aug 13;37(1):190.(浙江大学医学院第一附属医院)

24. Liao WQ, et al. Modulation of Macrophage Polarization by Human Glomerular Mesangial Cells in Response to the Stimuli in Renal Microenvironment. J Interferon Cytokine Res. 2018 Dec;38(12):566-577.(301医院 肾内科)

25. Li RX, et al. Expressway to Rheumatoid Arthritis by Macrophage-derived Microvesicle-Coated Nanoparticles. Nano Letters.2018 Dec;19:124–134.(复旦大学)

26. Huang H, et al. Kisspeptin/GPR54 signaling restricts antiviral innate immune response through regulating calcineurin phosphatase activity. Sci Adv. 2018 Aug 8;4(8):eaas9784.(华东师范大学 )

27. Wang G, et al. TFPI-2 suppresses breast cancer cell proliferation and invasion through regulation of ERK signaling and interaction with actinin-4 and myosin-9. Sci Rep. 2018 Sep 26;8(1):14402.(汕头大学医学院)

28. Jiang P, et al. Quantitative proteomics analysis of differentially expressed proteins in ruptured and unruptured cerebral aneurysms by iTRAQ. J Proteomics. 2018 Jun 30;182:45-52.(首都医科大学附属北京天坛医院)

29. Xiao-Pei H, et al. Systematic identification of Celastrol-binding proteins reveals that Shoc2 is inhibited by Celastrol. Biosci Rep. 2018 Nov 20;38(6):BSR20181233.(第二军医大学)

30. Zhang Z, et al. Potential biological functions of microvesicles derived from adenoid cystic carcinoma. Oncol Lett. 2018 May;15(5):7900-7908.(华西医院)

31. Bao Y, et al. Angiopoietin-like protein 3 blocks nuclear import of FAK and contributes to sorafenib response. Br J Cancer. 2018 Aug;119(4):450-461.(上海长征医院)

2017年:

1. Ling S, Xie H, et al. Metformin potentiates the effect of arsenic trioxide suppressing intrahepatic cholangiocarcinoma: roles of p38 MAPK, ERK3, and mTORC1. J Hematol Oncol. 2017 Feb 28;10(1):59.(浙江大学第一附属医院)

2. Chen Y, et al. Prodrug-Like, PEGylated Protein Toxin Trichosanthin for Reversal of Chemoresistance. Mol Pharm. 2017 May 1;14(5):1429-1438.(中科院药物所)

3. Ge Z, et al. Connexin 43 mediates changes in protein phosphorylation in HK-2 cells during chronic cadmium exposure. Environ Toxicol Pharmacol. 2017 Jul;53:184-190.(复旦公共卫生学院)

4. Wang A, et al. Long non-coding RNA ENST00462717 suppresses the proliferation, survival, and migration by inhibiting MDM2/MAPK pathway in glioma. Biochem Biophys Res Commun. 2017 Apr 1;485(2):513-521.(齐鲁医院)

5. Yang Y, et al. Antibody Array Revealed PRL-3 Affects Protein Phosphorylation and Cytokine Secretion. PLoS One. 2017 Jan 9;12(1):e0169665.(北大肿瘤医院)

6. Zhong C, et al. Coagulation factor XI vaccination: an alternative strategy to prevent thrombosis. J Thromb Haemost. 2017 Jan;15(1):122-130.(上海交通大学)

7. Cao Y, et al. B Lymphocyte Chemoattractant (CXCL13) Is an Indicator of Acute Gastrointestinal GVHD in Murine Model. Inflammation. 2017 Oct;40(5):1678-1687.(温州医科大学)

8. Sun HM, et al. PALLD Regulates Phagocytosis by Enabling Timely Actin Polymerization and Depolymerization. J Immunol. 2017 Sep 1;199(5):1817-1826.(上海交大医学院附属瑞金医院)

9. Shi F, et al. The dual PI3K/mTOR inhibitor dactolisib elicits anti-tumor activity in vitro and in vivo. Oncotarget. 2017 Dec 9;9(1):706-717.(上海交通大学)

2016年:

1. Lu H, et al. Plasma cytokine profiling to predict susceptibility to acute mountain sickness. Eur Cytokine Netw. 2016 Nov 1;27(4):90-96.(兰州军区总医院)

2. Yang F, et al. Curcumin protects ANIT-induced cholestasis through signaling pathway of FXR-regulated bile acid and inflammation. Sci Rep. 2016 Sep 14;6:33052. (上海中医药大学药学院)

3. Chen Y, et al. The hepatitis B virus X protein promotes pancreatic cancer through modulation of the PI3K/AKT signaling pathway. Cancer Lett. 2016 Sep 28;380(1):98-105.(浙江大学)

4. Zhu X, et al. Proinflammatory status in the aqueous humor of high myopic cataract eyes. Exp Eye Res. 2016 Jan;142:13-8.(复旦大学附属眼耳鼻喉科医院)

5. Gu C, et al. RalA, a GTPase targeted by miR-181a, promotes transformation and progression by activating the Ras-related signaling pathway in chronic myelogenous leukemia. Oncotarget. 2016 Apr 12;7(15):20561-73.(暨南大学)
 
6. Zhang Y, et al. GDF11 improves tubular regeneration after acute kidney injury in elderly mice. Sci Rep. 2016 Oct 5;6:34624.(301医院)

7. Liu X, et al. Genome Wide Association Study Identifies L3MBTL4 as a Novel Susceptibility Gene for Hypertension. Sci Rep. 2016 Aug 2;6:30811.(朝阳医院)

8. Kuang XY, et al. The phosphorylation-specific association of STMN1 with GRP78 promotes breast cancer metastasis. Cancer Lett. 2016 Jul 10;377(1):87-96.(复旦大学附属肿瘤医院)

9. Jiang HL, et al. SSBP1 Suppresses TGF-Driven Epithelial-to-Mesenchymal Transition and Metastasis in Triple-Negative Breast Cancer by Regulating Mitochondrial Retrograde Signaling. Cancer Res. 2016 Feb 15;76(4):952-64.(复旦大学附属肿瘤医院)

10. Gao Y, et al. Mammalian elongation factor 4 regulates mitochondrial translation essential for spermatogenesis. Nat Struct Mol Biol. 2016 May;23(5):441-9.(中科院生物物理所)

11. Zhu Y, et al. Long non-coding RNA LOC572558 inhibits bladder cancer cell proliferation and tumor growth by regulating the AKT-MDM2-p53 signaling axis. Cancer Lett. 2016 Oct 1;380(2):369-374.(复旦大学癌症中心)

12. Zhu R, et al. pH sensitive nano layered double hydroxides reduce the hematotoxicity and enhance the anticancer efficacy of etoposide on non-small cell lung cancer. Acta Biomater. 2016 Jan;29:320-332.(同济大学生命科学与技术学院)

13. Chen W, et al. The cytomegalovirus protein UL138 induces apoptosis of gastric cancer cells by binding to heat shock protein 70. Oncotarget. 2016 Feb 2;7(5):5630-45.(温州医科大学)

2015年:

1. Wang T, et al. XCR1 promotes cell growth and migration and is correlated with bone metastasis in non-small cell lung cancer. Biochem Biophys Res Commun. 2015 Aug 21;464(2):635-41.(长征医院)

2. Zhu XJ, et al. Molecular Inflammation in the Contralateral Eye After Cataract Surgery in the First Eye. Invest Ophthalmol Vis Sci. 2015 Aug;56(9):5566-73.(复旦大学附属眼耳鼻喉科医院)

3. Wei Y, et al. Bu-Shen-Yi-Qi formulae suppress chronic airway inflammation and regulate Th17/Treg imbalance in the murine ovalbumin asthma model. J Ethnopharmacol. 2015 Apr 22;164:368-77.(复旦大学附属华山医院)

4. Zhu YP, et al. Reactive stroma component COL6A1 is upregulated in castration-resistant prostate cancer and promotes tumor growth. Oncotarget. 2015 Jun 10;6(16):14488-96.(复旦大学肿瘤医院)

5. Luo LL, et al. Insulin-like growth factor binding protein-3 is a new predictor of radiosensitivity on esophageal squamous cell carcinoma. Sci Rep. 2015 Dec 16;5:17336. (中山大学癌症中心)

6. Zhang HN, et al. Systematic identification of arsenic-binding proteins reveals that hexokinase-2 is inhibited by arsenic. Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15084-9.(上海交大医学院附属瑞金医院)

7. Chen P, et al. Bone marrow stromal cells protect acute myeloid leukemia cells from anti-CD44 therapy partly through regulating PI3K/Akt-p27(Kip1) axis. Mol Carcinog. 2015 Dec;54(12):1678-85.(福建医科大学)

2014年:

1. You D, et al. Acetyl coenzyme A synthetase is acetylated on multiple lysine residues by a protein acetyltransferase with a single Gcn5-type N-acetyltransferase (GNAT) domain in Saccharopolyspora erythraea. J Bacteriol. 2014 Sep;196(17):3169-78.(华东理工大学生物反应器工程国家重点实验室)

2. Ding Y, et al. Protective effects of astragaloside IV on db/db mice with diabetic retinopathy. PLoS One. 2014 Nov 20;9(11):e112207.(南京医科大学第一附属医院)

3. Ding Y, et al. Seed-targeting anti-miR-21 inhibiting malignant progression of retinoblastoma and analysis of their phosphorylation signaling pathways. Exp Eye Res. 2014 May;122:1-8.(暨南大学医学院)

4. Rao W, et al. OVA66 increases cell growth, invasion and survival via regulation of IGF-1R-MAPK signaling in human cancer cells. Carcinogenesis. 2014 Jul;35(7):1573-81.(上海交通大学医学院)

5. Li W, et al. Downregulated miR-646 in clear cell renal carcinoma correlated with tumour metastasis by targeting the nin one binding protein (NOB1). Br J Cancer. 2014 Sep 9;111(6):1188-200. (上海市第十人民医院)

6. Dai Z, et al. Capn4 contributes to tumour growth and metastasis of hepatocellular carcinoma by activation of the FAK-Src signalling pathways. J Pathol. 2014 Nov;234(3):316-28.(复旦大学中山医院肝癌研究所)

7. Ma J, et al. Depletion of intermediate filament protein Nestin, a target of microRNA-940, suppresses tumorigenesis by inducing spontaneous DNA damage accumulation in human nasopharyngeal carcinoma. Cell Death Dis. 2014 Aug 14;5(8):e1377.(暨南大学)

8. Jia D, et al. Amplification of MPZL1/PZR promotes tumor cell migration through Src-mediated phosphorylation of cortactin in hepatocellular carcinoma. Cell Res. 2014 Feb;24(2):204-17.(复旦大学附属肿瘤医院)

9. Fan Q, et al. Identification of proteins that interact with alpha A-crystallin using a human proteome microarray. Mol Vis. 2014 Jan 14;20:117-24.(复旦大学附属眼耳鼻喉科医院)

2013年:

1. Xu N, et al. Activation of RAW264.7 mouse macrophage cells in vitro through treatment with recombinant ricin toxin-binding subunit B: involvement of protein tyrosine, NF-κB and JAK-STAT kinase signaling pathways. Int J Mol Med. 2013 Sep;32(3):729-35.(军事医学科学院军事兽医研究所)

2. Li F, et al. Superoxide mediates direct current electric field-induced directional migration of glioma cells through the activation of AKT and ERK. PLoS One. 2013 Apr 16;8(4):e61195.(重庆西南医院)

3. Cui WY, et al. Identification and characterization of poly(I:C)-induced molecular responses attenuated by nicotine in mouse macrophages. Mol Pharmacol. 2013 Jan;83(1):61-72.(浙大)

2012年:

1. Zhang YM, et al. A novel angiogenesis inhibitor impairs lovo cell survival via targeting against human VEGFR and its signaling pathway of phosphorylation. Cell Death Dis. 2012 Oct 11;3(10):e406.(西安交通大学医学院)

2. Fan H, et al. Cardioprotective effects of salvianolic Acid a on myocardial ischemia-reperfusion injury in vivo and in vitro. Evid Based Complement Alternat Med. 2012;2012:508938.(烟台大学药学院)

2011年:

1. Li H, et al. Increased prevalence of regulatory T cells in the lung cancer microenvironment: a role of thymic stromal lymphopoietin. Cancer Immunol Immunother. 2011 Nov;60(11):1587-96.(天津医科大学肿瘤医院)


 

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